| Introduction Scars, particularly those on the face, exert a profound psychological impact on affected individuals. Conventional modalities for scar revision—such as autologous fat injections, dermal grafts, and synthetic fillers—are often constrained by their invasiveness, expense, and the need for specialized infrastructure and expertise. In this context, biofillers have re-emerged as a viable alternative. Platelet-poor plasma (PPP) gel, obtained from the patient’s own blood, can be used as a natural “biofiller,” offering both immediate volumetric enhancement and stimulation of neocollagenesis, thereby improving atrophic scars in a minimally invasive manner. Aim: To evaluate the efficacy of biofillers in the management of atrophic scars. Methodology: Two patients with post-traumatic scars and one patient with post-acne scarring refractory to fractional laser therapy were enrolled. A volume of 10 mL venous blood was drawn into a sodium-citrate bulb and centrifuged at 3200 rpm for 8 minutes to obtain platelet-rich plasma. The plasma was further centrifuged at 1000 rpm for 5 minutes in a plain bulb to yield PPP. This was incubated at 100°C for 5 minutes, followed by cooling at 7–10°C for 5 minutes, resulting in the formation of PPP gel. The biofiller was injected beneath the scars, and outcomes were assessed using the Visual Analogue Scale (VAS). Results and Conclusion: All three patients demonstrated grade 2 improvement in VAS at 3 weeks post-treatment. The findings underscore that biofiller, though a relatively old technique, remains simple, safe, cost-effective, and devoid of immunogenic risk. It holds promise as a practical and patient-acceptable option, potentially serving as an alternative or adjunct to synthetic fillers in scar revision therapy. It may serve as an effective means to increase patient’s acceptance of synthetic fillers. |
